Much like your favorite shirt, over time, your body will wear out.  You will probably not end up with holes throughout your skin in random places, but your muscles will get tight, torn and lose range of motion.

Lets look at the shirt for a moment.  This is your favorite shirt.  You wear it as often as you can get away with, even if that is just at home.  The more you wear it, the more you wash it.  The more you wash it, the more the material thins.  The more the material thins, the more likely you are going to have holes begin to appear.